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What is Intravenous Immunoglobulins?
Intravenous immunoglobulin (IVIG) is a medication complete from pooled antibodies donated by healthy people. It is given intravenously (through a vein) to treat a variety of conditions, including:
Primary immunodeficiency diseases, such as
agammaglobulinemia and common variable immunodeficiency
Autoimmune illnesses, such as universal lupus erythematosus,
rheumatoid arthritis, and Guillain-Barré syndrome
Inflammatory diseases, such as Kawasaki disease and chronic
inflammatory demyelinating polyneuropathy
Idiopathic thrombocytopenic purpura (ITP), a condition in
which the body destroys its own platelets
Some types of cancer, such as manifold myeloma and chronic
lymphocytic leukemia
IVIG works by providing antibodies that the body is not
making on its own. These antibodies can help to fight infections, suppress the
immune system, and reduce inflammation.
IVIG is typically given as a series of infusions, once or
twice a month. The dosage and frequency of treatment vary depending on the
condition being treated.
The most common side effects of IVIG are headache, fever,
chills, and nausea. More serious side effects, such as kidney problems and
blood clots, are rare.
IVIG is a safe and real treatment for a variety of
conditions. However, it is important to discuss the risks and benefits of IVIG
with your doctor before starting treatment.
Here are some additional details about the action of
IVIG:
IVIG modulates the activation and effector purposes of B and
T lymphocytes, which are white blood cells that play a role in the resistant
system.
IVIG neutralizes pathogenic autoantibodies, which are
antibodies that attack the body's own tissues.
IVIG interferes with antigen presentation, which is the
process by which the body's cells present foreign antigens to the immune system.
IVIG has a strong anti-inflammatory effect, which may be due
to its interaction with the complement system, cytokines, and endothelial
cells.
IVIG is a complex medication with a variety of mechanisms of
action. It is important to consult with a doctor to understand how IVIG works
and how it can benefit you.
Why immunoglobulin injection is given?
Immunoglobulin injection is given for a variety of reasons,
including:
To treat primary immunodeficiency diseases, which are
conditions in which the body does not make enough antibodies.
To treat autoimmune diseases, which are conditions in which
the body's immune system attacks its own tissues.
To treat inflammatory diseases, such as Kawasaki disease and
chronic inflammatory demyelinating polyneuropathy.
To prevent or treat infections in people who are at high
risk, such as those with cancer or who have undergone organ transplantation.
To reduce the risk of rejection after structure
transplantation.
To treat ITP, a condition in which the body destroys its own
platelets.
To treat some types of cancer, such as multiple myeloma and
chronic lymphocytic leukemia.
Immunoglobulin injection is given as an infusion into a
vein. The dosage and frequency of treatment vary depending on the condition
being treated.
The most common side effects of immunoglobulin injection are
headache, fever, chills, and nausea. More serious side effects, such as kidney
problems and blood clots, are rare.
Immunoglobulin injection is a safe and effective treatment
for a variety of conditions. However, it is important to discuss the risks and
benefits of immunoglobulin injection with your doctor before starting
treatment.
Here are some additional details about the reasons for
immunoglobulin injection:
Primary immunodeficiency diseases: These are conditions in
which the body does not make enough antibodies. Antibodies are proteins that
help the body fight infection. People with primary immunodeficiency diseases
are at increased risk for infections, including serious infections that can be
life-threatening. Immunoglobulin injection can help to provide the body with
the antibodies it needs to contest infection.
Autoimmune diseases: These are conditions in which the
body's resistant system attacks its own tissues. Immunoglobulin injection can
help to suppress the immune system and reduce the inflammation that is
associated with autoimmune diseases.
Inflammatory diseases: These are conditions that cause
inflammation in the body. Immunoglobulin injection can help to reduce
inflammation and improve symptoms.
Prevention of infections: Immunoglobulin injection can be
used to prevent infections in people who are at high risk, such as those with
cancer or who have undergone organ transplantation.
Reduce the risk of refusal after organ transplantation:
Immunoglobulin injection can help to reduce the risk of rejection after organ
transplantation. This is because it can help to suppress the immune system and
prevent it from aggressive the transplanted organ.
Treat ITP: ITP is a condition in which the body destroys its
own platelets. Also, are blood cells that help to clot blood. People with ITP
are at increased risk for bleeding. Immunoglobulin injection can help to
increase the number of platelets in the blood and reduce the risk of bleeding.
Treat some types of cancer: Immunoglobulin injection can be
used to treat some types of cancer, such as multiple myeloma and chronic
lymphocytic leukemia. This is because it can help to suppress the immune system
and prevent it from aggressive the cancer cells.
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